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We further assessed other intracellular antioxidant defenses, including catalase, vitamin E and the master antioxidant response transcription factor Nrf2 (Fig.5)

In fact, carotenoid biosynthesis is controlled by specific enzymes, and compounds that inhibit these enzymes are used to adapt and enhance the expression of the relevant enzymes 9

For patients managing the unpredictable and overlapping symptoms of Long COVID, ME/CFS, and dysautonomia, supplementing with a highly bioavailable form of ALA may help manage several debilitating specific symptoms

Desjardins, P., Frost, E