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Q4: Does melasma ever fully go away

Exclusion criteria included: studies that did not focus on GPX4s role in pain modulation

Patient 2 is a 35-year-old female with focal unaware seizures from right hemisphere with whole-cerebral spread status post long-term vagal nerve stimulator placement in 2013 (6 years prior to the current study) and no prior surgical intervention, currently on lamotrigine, carbamazepine, and topiramate

References 1 DelgoffeGM

Resistance to cisplatin, but not oxaliplatin, appears to be partly mediated through loss of function in the MMR proteins (hMLH1, hMLH2, or hMSH6), which recognize platinum-DNA adducts and initiate apoptosis