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These correlations show that 2D and 3D culture models of MNA behave very similarly in terms of drug responses, which validates drug screening in 2D cultures as not only as convenient but also meaningful method for finding new therapies for MNA

Ginekol Pol (2015) 86:93239

These observations underscore the critical importance of maintaining a dynamic and balanced ratio of oestrogen to progesterone for womens health, particularly for preserving brain health as they age 41

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These compensations can offset or even override the initial vasodilating effect