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Freezing damages B12, and a frozen vial should be discarded

No age-specific dosing guidelines exist in published research

Pressure in lower esophageal sphincter (but not in pyloric sphincter) L-arginine further decreased, L-NAME also further decreased while L-NAME + L-arginine rats presented similar results as controls

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It is also of clinical benefit to some patients with -thalassemia intermedia and it reduces the need for transfusions in a subset of individuals with -thalassemia major [46], [47], [48], [49], [50], [51], [52], [53]