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NA-Cis-AuNRs suppress angiogenic factors in the tumor microenvironment model To further validate the role of angiogenic transcription factors in the above experiment, RNA was isolated from developing CAM blood vessels and analyzed by RT-qPCR to assess the expression of key angiogenic transcription factors, suggesting their role in promoting the proliferation of endothelial cells and the formation of capillary-like structures

Providers typically monitor response over time using symptoms, labs when appropriate, and safety assessments according to clinical guidance

Safety can thus be assessed e.g

Mei M, Zhao L, Li Q, Chen Y, Huang A, Varghese Z, Moorhead JF, Zhang S, Powis SH, Li Q, Ruan XZ (2011) Inflammatory stress exacerbates ectopic lipid deposition in C57BL/6J mice