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The trial enrolled 3,417 individuals who are either obese or overweight and have one or more comorbid conditions, with an average baseline body weight of 106.9 kg

10.1097/fbp.0b013e32833a5bf4 60 LanB.GeJ.-W.ChengS.-W.ZhengX.-L.LiaoJ.HeC.et al (2020)

Mutations in the Ldlr gene are the most common cause of familial hypercholesterolemia (FH), an autosomal dominant disorder associated with elevated levels of LDL-C and increased risk for premature cardiovascular disease (218)

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