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Following the successful RCT with dupilumab in BP (see above), it needs to be determined whether IL-13 inhibition is equivalent or even more favorable compared with dual IL-4/IL-13 inhibition in BP

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Besides, the decreases in protein levels of GluA1, brain-derived neurotrophic factor (BDNF) and postsynaptic density protein 95 in the prefrontal cortex caused by CSDS in mice could be reversed by ISA (Wang et al., 2023)

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