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H., Gonalves, J

Its contraindicated during pregnancy or breastfeeding and has controversial regulatory status in some countries where its restricted or banned

doi: 10.1038/s41392-023-01367-x 11 RaisRLembergKMTenoraLArwoodMLPalAAltJet al

23 Some of the proteins released from mitochondria into the cytoplasm include apoptosis-inducing factor and endonuclease G, both of which have nuclear localization signals and thus translocate to the nucleus, where the endonuclease cleaves DNA, resulting in DNA fragmentation

however, in a previous interim analysis, the authors reported that a protective effect was perceived more clearly in female individuals than in male individuals [107]