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To be more specific, the decrement in the expression of synaptophysin and the synaptic vesicle recycling increment induced by alpha-synuclein can be attenuated by TQ, hence protects against synaptic toxicity in primary hippocampal and hiPSC neurons of rats

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doi: 10.1038/nm.2609 83 EngelmanJAMukoharaTZejnullahuKLifshitsEBorrsAMGaleCMet al

A 2019 review in Hormone and Metabolic Research documented these outcomes, while the landmark STEP 1 trial (Wilding et al., NEJM 2021) established 14.9% average weight reduction with semaglutide with direct relevance to androgen-driven conditions where adipose tissue is itself a hormonal organ

Dietary modifications can also be beneficial