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It may even contribute to certain health conditions, including cancer, heart disease, and diabetes ( Promisingly, studies show that piperine could possess powerful anti-inflammatory properties to help keep chronic inflammation at bay ( For instance, one test-tube study showed that piperine extract helped protect skin cells against ultraviolet (UV)-induced skin damage and inflammation ( In another test-tube study, piperine blocked the production of several markers of inflammation in brain and spinal cord cells ( Several older animal studies also suggest that piperine could reduce inflammation associated with conditions like arthritis and asthma ( However, further research is needed to determine how piperine supplements, including BioPerine, affect inflammation in humans

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They also may activate platelets

PMID: 24796079

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