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For instance, moderate acoustic trauma may lead to detachment or degeneration of high-threshold cochlear fibers from their corresponding inner hair cells

Microglia express multiple receptors that recognize different types of stimuli and mediate activation of Toll-Like Receptors (TLRs) and Triggering Receptor Expressed on Myeloid cells 2 (TREM2), with the latter attracting considerable interest since GWAS studies identified multiple TREM2 variants associated with an increased risk of developing AD [133136]