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Hepatic CP activity was significantly lower in Aadac KO mice than that in WT mice, resulting in elevated hepatic ferrous iron levels in Aadac KO mice

USA 113 (34), E4966E4975

We can hypothesize that apoC1 may have different functions according to its distribution between lipoproteins (with a pro-atherogenic effect when associated with VLDL and an anti-atherogenic effect when associated with HDL) and that qualitative changes of apoC1 occurring in clinical situations as diabetes and atherosclerosis may also modify its properties and expression pattern

The local production of IGF-1 is controlled primarily by GH and other hormones (e.g., parathyroid and thyroid hormones) (Bikle et al., 2009)

Febbraro F, Andersen KJ, Sanchez-Guajardo V, Tentillier N, Romero-Ramos M