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Eur J Pharm Sci 42:7380 Xin W, Zhang L, Sun F, Jiang N, Fan H, Wang T, Li Z, He J, Fu F (2011b) Escin exerts synergistic anti-inflammatory effects with low doses of glucocorticoids in vivo and in vitro

It occurs due to aging, environmental pollution, exposure to tobacco smoke, alcohol, UV radiation, and dozens of other small factors that add up over time

Considering that ALA could effectively stabilize hepatic Fe 2+ expression (Figure 1), and depress both levels of ferroptotic (Figure 2) and pro-apoptotic signaling (Figure 6), dietary supplementation with ALA may thus serve as a useful and practical way to prevent, or further counteract the CSD-induced liver injury and metabolic deficiency

Conclusion: Through this study, we conducted a comprehensive analysis of NAFLD alterations, exploring the gut microbiota, genes and metabolites of the results offer insights into the speculated biological mechanisms underlying NAFLD

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