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doi: 10.1016/j.arcmed.2017.03.014 168 LiuJShiYWuMXuMZhangFHeZet al

When oxidised, it forms the disulfide GSSG that can be reduced back to GSH by the glutathione reductase (GR)

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This review examines recent progresses in the preclinical and clinical development of targeting dysregulated cell death pathways for cancer treatment