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Peivandi, S., Karimpour, A., and Moslemizadeh, N

Furthermore, the evidence remains inconsistent, as the potential benefits of TRT are often accompanied by other iatrogenic effects, including erythrocytosis, benign prostatic hyperplasia, gynecomastia, and an increased risk of prostate cancer [178, 179]

In particular, during progression of glaucoma, astrocytes are involved in the remodelling of the lamina cribrosa and they could act as initiators of the pathology