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The possibility of being able to release controlled growth factors from the biomaterial during spinal fusion also makes biomaterials an attractive solution (Gupta et al., 2015)

3.3 Progestogens The main natural progestogen, progesterone (P4), is synthesized from cholesterol by the cholesterol side-chain cleavage enzyme and 3-hydroxysteroid dehydrogenase (122)

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These bioactivities not only provide mechanistic insights into the physiological relevance of collagen peptides but also serve as the foundation for their integration into functional foods targeting oxidative stress, hypertension, and metabolic disorders

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