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The highest enriched genes involved in mitochondrial translation were the RNA-binding protein C6ORF203 / MTRES1 and METTL17 , the rRNA-modifying enzymes GTPBP3 , functionally related GTPBP8 , the oligoribonuclease REXO2 and the mitochondrial release factor C12ORF65 / MTRFR (Fig
A DNase I delivery system that mimics the inflammatory chemotactic effect of neutrophils has been shown to effectively prevent inflammatory damage to lung tissues in an LPS-induced acute lung injury mouse model (124), suggesting that targeting NETs to alleviate acute lung inflammation is also a feasible approach
The peptide also promotes tissue remodeling by regulating matrix metalloproteinases, ensuring damaged collagen is removed while new, healthy collagen is formed
Circulation 25:493505 Campuzano V, Montermini L, Molto MD, Pianese L, Cossee M, Cavalcanti F, Monros E, Rodius F, Duclos F, Monticelli A, et al (1996) Friedreichs ataxia: autosomal recessive disease caused by an intronic GAA triplet repeat expansion
