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For example, in 2024, asylees and refugees contributed an estimated $581 billion in revenue to federal, state, and local governments over a 15-year period, strengthening the case for improved access to asylum as communities nationwide, especially in rural areas, continue to feel economic strain

[102] Surgery [edit] If medical treatment is not effective, surgery may be performed

MOTS-c can translocate into the nucleus in response to metabolic stress and regulation of adaptive nuclear gene expression

Thiazolides inhibit growth and induce glutathione-S-transferase Pi (GSTP1)-dependent cell death in human colon cancer cells