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The compound is administered to damaged tissue and assessed against an injured control group

The deficiency causes a reduction in red blood cell production, which results in anemia and a reduced oxygen supply to tissues and organs

mRNA and protein levels of CLOCK and BMAL1 were down-regulated in insulin-resistant primary mouse hepatocytes [31] and C2C12 myotubes [46], while ectopic expression of CLOCK and BMAL1 proteins increased insulin sensitivity