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Overall, the results suggest a narrower therapeutic margin for MDA compared with MDMA and indicate that lysine conjugation of MDA may be a viable strategy to modify the time course of effects, though not necessarily to enhance overall tolerability

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Effect of subcutaneous casirivimab and imdevimab antibody combination vs placebo on development of symptomatic COVID-19 in early asymptomatic SARS-CoV-2 infection: a randomized clinical trial