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Tannins significantly reduced the phase I and phase II enzyme activities in mouse liver tissues ( Salvianolic acid B, a rosmarinic acid dimer, is an active component of Salvia miltiorrhiza Bunge [Lamiaceae], and its reduction of drug-induced liver injury is associated with its antioxidant activity ( Chlorogenic acid, a phenolic compound with various biological activities, ameliorates liver injury in an experimentally induced model of oxidative stress ( Caffeic acid is a common phenolic chemical found in a wide variety of plants

This method bypasses liver metabolism, enhancing bioavailability and ensuring better absorption of its active components, resulting in higher efficacy

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Peripheral blood lymphocyte apoptosis profiles were done at the onset and after six months of treatment