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Other important examples of drugs that can induce mitochondrial dysfunction are retroviral nucleoside analogs in HIV infection, as well as salicylates that can alter the hepatic mitochondria in Reye syndrome

However, larger and longer-term studies are needed to confirm the results

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(5) Other regulatory molecules or factors acting on SIRT1 Upstream of SIRT1, in addition to miRNAs, a novel fibroblast growth factor 1 variant could counteract adriamycin-induced apoptosis by decreasing p53 activity via upregulation of SIRT1-mediated p53 deacetylation