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Perform small pilot titrations to identify the linear response window for your assay rather than assuming a single working concentration

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Excessive methylglyoxal is detoxified in part by glyoxalase I, which converts methylglyoxal into S-D-lactoylglutathione in the presence of glutathione (Inoue and Kimura, 1996)

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doi: 10.1002/dta.183

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Understanding the pharmacokinetic behaviour of HTY is essential for interpreting its biological effects and translational relevance

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Clearance of bilirubin from rat brain after reversible osmotic opening of the blood-brain barrier

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