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Clinical Update 2/16/2019 Energy Drinks & Aggression Are people who frequently consume energy drinks (like 5-hour Energy) more likely to be aggressive or have mental health problems

Neohesperidin (NHP) can inhibit macrophage migration into target tissues and decrease pro-inflammatory cytokine levels, including TNF-, IL-1, IL-6, and COX-2, at both mRNA and protein levels, exceeding that of mesalazine at similar concentrations (173)

Whilst air bubbles in subcutaneous injections pose no safety risk, removing larger bubbles before injection helps ensure accurate dosing