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The acquired genetic alterations confer upon the initially transformed atypical melanocytes and later upon the melanoma cells that evolved, a selective advantage over their neighbouring normal cells in terms of fitness and proliferation

Applications Pigmentation & Photoprotection Studies: Model melanin synthesis pathways, UVdamage mitigation, and cosmetic formulation testing in skin explants and organotypic cultures PubMed

Most of the information on the physiology of oral mucosal melanocytes is derived from research on epidermal melanocytes

doi:10.1097/AOG.0000000000003514 Clayton AH, Althof SE, Kingsberg S, et al

Proc Natl Acad Sci U S A