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Nonalcoholic fatty liver disease is exacerbated in high-fat diet-fed gnotobiotic mice by colonization with the gut microbiota from patients with nonalcoholic steatohepatitis

In line with this, various experiments using cell cultures, transgenic mice, and preclinical models revealed protective effects of antioxidants (Polidori and Nelles 2014

In mammals, GPX family members can utilize GSH as a reducing agent in combating oxidative stress and maintaining redox balance via a different mechanism of action and site of action

Notably, the spleen has recently been identified as a cryptic erythrocytic reservoir during natural infections, harbouring a substantial parasite biomass [1]

doi: 10.1007/s10522-013-9416-9 72 KorosecAFrechSGesslbauerBVierhapperMRadtkeCPetzelbauerPet al