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Autoantibodies which interfere with the function of the folate receptor alpha called folate receptor alpha autoantibodies have been identified in 58%-76% of children with ASD and independent studies have demonstrated that blood titers of these autoantibodies correlate with folate levels in the cerebrospinal fluid

Nutrients , 5(2), 525542

Citing MMDB Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH

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Such roles, which include uremic toxins production, alteration of metabolic pathways, and modulation of inflammation and oxidative stress, influence CKD pathogenesis (Pires et al., 2024)