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Epitalon, MOTS-c, SS-31, and Humanin are peptides short amino-acid chains that act as signals

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Here, we evaluate common challenges including assumed readiness of individuals to respond, lack of information on the animals physiological and social status, their pre-experimental cue exposure, the innate or learned character of the responses, the animals acclimation and habituation status, and the impact of the animals upon their own environment