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It should be noted that pathophysiological changes in the brain occur decades before the onset of AD symptoms, which makes diagnosis and successful treatment of the disease even more challenging (Hof et al., 1996

1 Introduction Liver disease, a globally widespread disease accounting for 4% of the global death toll each year, is a serious challenge to peoples health in different regions with numerous risk factors such as viral infections, excessive alcohol consumption, unhealthy diet, and drug injury ( Recently, there has been a growing focus on natural products as complementary and alternative medicine for both preventing and treating liver diseases ( Phyllanthus encompasses a vast array of species, with over 1,000 species contain more than 500 bioactive metabolites

Substantial enzymatic or non-enzymatic modification of proteins driving inflammation has gained a lot of interest in recent years

Penyakit kronis tersebut biasanya baru muncul setelah bertahun-tahun radikal bebas menyerang tubuh

6.Clinical Implications and Therapeutic Potential Eicosanoids as Drug Targets Eicosanoids have long been recognized as important mediators of inflammation and immune responses, making them attractive targets for drug development