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However, the substantial structural changes that occur in the development of the IVD and the inherent heterogeneity of the fully formed NP, including the differences in cell population between mouse and human samples have made distinctly defining the ultimate mature NP cell profile a difficult task

Notably, this pathological network is no longer confined to the central nervous system but propagates and amplifies systemically through pathways such as the gut-brain and spleen-brain axes, providing a new perspective for understanding PD as a systemic disorder

3.5 Histological and Immunohistological Analysis of Implanted BP The BP explants were taken out after 8 weeks, fixed with paraformaldehyde, ehydrated, and embedded in paraffin

1 2 European Urology