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By coupling mechanistic insight with materials design, this review highlights the potential of smart hydrogels to deliver microenvironment adaptive, multitarget interventions and aims to support rational optimization of new materials and progress toward clinical

the test mouse was placed in the centre and allowed to explore the objects for 10 min

[DOI] [PubMed] [Google Scholar] 663.Keira N, Tatsumi T, Matoba S, Shiraishi J, Yamanaka S, Akashi K, Kobara M, Asayama J, Fushiki S, Fliss H, Nakagawa M

Improvements in blood glucose and lipid parameters were also observed in trial settings

By employing an isotope labeling scheme using 2- 2 H-lactate 27,28 , we found that more than 95% of lactate in the mitochondria of AR MCF7 cells was 2 H-labeled, and that the 2 H-labeled lactate in the mitochondria of AR MCF7 cells was significantly higher than that in Ad cells (Fig