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Statistical analysis For metabolomic analysis, metabolites were normalized with ribitol (internal standard), with logarithmic transformation and autoscaling to proceed with the statistical analysis

The interaction is typically mild but may require dose adjustments for some patients

They also play important roles in a variety of metabolic functions

Bread cofortified with folic acid and vitamin B-12 improves the folate and vitamin B-12 status of healthy older people: a randomized controlled trial