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Clinical studies suggest collagen supplementation may help: reduce knee osteoarthritis pain improve joint function support tendon rehabilitation when combined with exercise Examples of Osteoarthritis studies: Examples of Tendon studies: Unlike injectable peptides, collagen supplements function as nutritional support, not pharmacologic signaling molecules

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Here are some other ways to reduce discomfort, if needed (Usach, 2019): Ask your healthcare provider if you can apply a topical anesthetic, like benzocaine, before injection

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