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Trends Mol Med 26(7):630638

The development of polyploidy and its pattern vary among strains

It works by inhibiting the NNMT enzyme, which is associated with fat storage, insulin resistance, and reduced cellular energy

doi:10.1016/j.nut.2020.110991

Recently, a large genome wide association meta-analysis was conducted for serum FT4 levels, and a single nucleotide polymorphism in DIO1 was one of the five genome wide significant hits (65) strongly suggesting an important role for D1 in peripheral thyroid hormone metabolism in humans as well