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The enzyme l-GalDH generates cytosolic NADH, which has to be re-oxidized to allow the availability of NAD + and therefore sustain the reaction ( Figure 3 )

Free Radic Biol Med 49:19561968 Ji L, Chauhan A, Brown WT, Chauhan V (2009) Increased activities of Na+/K+-ATPase and Ca2+/Mg2+-ATPase in the frontal cortex and cerebellum of autistic individuals