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da Cunha Martins A Jr., Carneiro MFH, Grotto D, Adeyemi JA, Barbosa F Jr

Taking too much vitamin B12 can lead to skin rashes, digestive problems, anxiety, and heart palpitations.

As fat tissue grows and more NNMT is produced, higher amounts of hormones and pro-inflammatory signals are produced that are responsible for weight gain and other chronic diseases such as type 2 diabetes and cardiovascular disease. NNMT is responsible for converting nicotinamide (NA) into 1-methylnicotinamide (1-MNA), which takes it out of the NAD salvage pathway (see the diagram below)

While animal-based foods are naturally rich in vitamin B12, many plant-based foods and breakfast cereals are fortified to help people meet their needs