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Zhu et al., 2015

Data from the ironXS high school screening program showed that individuals identified with HFE p.Cys282Tyr homozygosity in late adolescence are very unlikely to have dangerously high body iron levels as measured by serum ferritin [103]

The observed similarity between plant and archaeal GDHs [30] and the regulatory diversity among phycomycete GDHs [29], collectively demonstrate the conserved, yet evolutionarily adaptable nature of this enzyme family, reflecting both fungal phylogeny and metabolic specialization

Therefore, for optimal results, injection is generally recommended