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For instance, some PD patients take amine oxidase inhibitors or anticholinergics that alter gut motility and bacterial growth [172]

Microecological preparations participate in regulating ferroptosis in IBD Probiotics Probiotics are live microorganisms that regulate immune responses, increase mucosal IgA production, and have a positive impact on the intestine [147]

Notably, the deletion of Gclc in tumours did not affect their growth (Fig

For instance, in mouse embryonic stem cells, targeted disruption of glucose-6-phosphate dehydrogenase, which is the rate-limiting enzyme in the pentose phosphate pathway, the predominant metabolic pathway for the generation of NADPH (a cofactor of GR), renders cells extremely sensitive to H 2 O 2 -induced cell death 34