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First developed as a mucolytic, NAC is now recognized for broader antioxidant, anti-inflammatory, immunomodulatory, and anti-biofilm effects, prompting its use as an adjuvant in treatment of chronic respiratory conditions

The result demonstrated that the extracts inhibited the growth and survival of the tested bacterial strains (351)

For instance, ROS-mediated damage impairs the function of immune cells, reducing their ability to effectively combat infections while simultaneously promoting chronic inflammation ( 3.2 Immune cell dysfunction and the gut-kidney axis in CKD Immune cell dysfunction is a key driver of CKD progression (Figure 2), involving abnormalities in adaptive and innate immune cells, including T cells, B cells, and monocytes/macrophages

A small number of NSCs remain in adults even if most of them are quiescent (recently reviewed in Zhao and Moore, 2018)

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