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Additional studies using other synthetic analogs of PregS revealed that a negatively charged moiety at the C3 position is, however, essential for positive modulation of NMDARs ( 2+ ([Ca 2+ ]i)-dependent and non-canonical mechanism involving G-proteins (Figure 2)

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The impact of COVID-19 has been unsurpassed thus far, and its long-term effects might be far more disastrous [3, 4]

10.1038/s41580-020-00314-w Nat