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Such benefits were made evident in a 2018 study in aged mice, in which eight weeks of SS-31 treatment was able to reverse age-related decline in mitochondrial ATP production, allowing for improvements in subjects exercise tolerance and a restoration of redox homeostasis (a balance between pro-oxidants and antioxidants that promotes proper muscle generation and function).24 25 Glaucoma Glaucoma, one of the leading causes of blindness globally,26 is a group of eye conditions characterized by damage to the retinal ganglion cells (RGCs).27 Since oxidative stress and mitochondrial dysfunction appear to contribute to RGC death, researchers have looked to SS-31 as a potential glaucoma treatment

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These results suggest that reduced homocysteine causes protein thiol homocysteinylation that may induce smooth muscle cell proliferation by binding to a redox receptor and that may exacerbate atherosclerotic lesion formation by inducing collagen expression (Tyagi, 1998)

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Azari AA, Barney NP

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This overly simplified response logic may lead to premature activation of the material, non-specific release or failure at critical moments

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