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Pharmacol Rep 58:399404 Skibska B, Goraca A, Skibska A, Stanczak A (2022) Effect of alpha-lipoic acid on rat ventricles and atria under LPS-Induced oxidative stress

Through transcriptomic profiling, histological analyses, and functional assessment, we demonstrate that antioxidant-driven tissue remodeling enhances epithelialization, neovascularization, and extracellular matrix organization, thereby improving graft stability and biomechanical properties

At the transcriptional level, ketogenesis is regulated by many factors, with peroxisome proliferator-activated receptor alpha (PPAR) exerting a fundamental role as it orchestrates the transcription of genes involved in fatty acid transport, uptake and oxidation, as well as the synthesis and import of ketone bodies (Kersten et al., 2000

2020;16(1): e1008208

RD: Writing review & editing