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Briefly, plasmid pool was used to generate a lentiviral library, which was transfected into HEK-293T cells and used to generate viral supernatant as described above

Tet3, the most highly expressed TET in the brain, is activity-dependent in primary cortical neurons [53]

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Summary: Evidence linking vitamin B12 deficiency directly to white or grey hair is limited, with hair greying predominantly determined by genetics and ageing rather than nutritional factors