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In 2000, it was acquired by the Faithful Central Bible Church and was used for church services and leased for concerts and sporting events until 2012, when it was purchased by the Madison Square Garden Company and underwent a $100 million renovation, reopening in 2014

The identification of breast cancer susceptibility genes BRCA1/2 , whose proteins are involved in DNA repair through homologous recombination, 106,107 has shed light on some mechanisms behind sporadic and hereditary breast cancers

Mol Genet Metab Rep

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Although this view was later attenuated based on the head-to-head conformation of the DNA-bound DBD dimer that was observed in X-ray crystallography studies and observations of relaxed response element stringency for selective chromatin binding [51, 52], it did point to the potential of variability in the composition of AREs and to deviations from the ideal 15 bp sequence