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The classic motor symptoms applied to diagnose PD patients include rest tremor, muscular rigidity, bradykinesia, and postural impairment (Gibb and Lees, 1988)

Detrick, Frederick, MD, USA Specialty section: This article was submitted to Neuroendocrine Science, a section of the journal Frontiers in Endocrinology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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