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Loss of PON1 also reduces HDLs ability to prevent oxidation of its own lipids and proteins, which has been reported in metabolic syndrome as oxidation of apoA-I impairs HDLs RCT and anti-inflammatory functions (865)

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Preliminary findings suggest that it may play a role in signaling processes associated with circulation dynamics in controlled settings

As for the effect of this oxidative stress on fertility, several studies have shown that between 30 and 80% of male sterility problems are caused by the presence of ROS in semen

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