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Anxiety disorders are documented and categorized in diagnostic systems such as the American Psychiatric Associations Diagnostic and Statistical Manual of Mental Disorders (DSM, now version IV-TR) or the International Classification of Diseases (ICD) (ICD, current version 10, World Health Organization) (19)

Summary Keywords bioavailability, ellagic acid, ellagitannins, pharmacokinetics, polyphenols, punicalagin, TMA Citation Haarhuis JE, Ahn-Jarvis J, Savva GM, Day-Walsh PE, Ferns C, Hughes S, Triller S, Al-Jaibaji O, Philo M, Acaroz E, Perez-Moral N and Kroon PA (2026) Effect of a polyphenol-rich pomegranate extract on plasma trimethylamine N-oxide levels following an oral carnitine challenge: a randomized controlled crossover trial in healthy adults

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The co-founders include former CDRH Director Jeff Shuren, CDRH Chief Scientist and Deputy Director Douglas Kelly, and Ross (Rusty) Segan, director of the Office of Product Evaluation and Quality (OPEQ)

Redox regulation of mitochondrial ATP synthase