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To examine numbness, we used a modified protocol of the adhesive removal test 36,47

A milestone in LHON treatment has been the approval of idebenone in 2015 ( Idebenone is a synthetic short-chain analogue of ubiquinone with anti-oxidant properties [10], which has shown to increase the rate of visual recovery in LHON patients, especially when given in the acute stage [11, 12]