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Both primary HSCs isolated from Cygb-deficient mice and those isolated from wild-type mice, in which Cygb mRNA was silenced, exhibited increased ROS generation and upregulated collagen alpha1(I), TIMP-1, IL-6, and TNF expression [29]

The combined reductions in cardiac output and peripheral vascular resistance ultimately lower systemic blood pressure (BP)

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Biological consequences of MHC-II expression by tumor cells in cancer