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In the first step, carbamoyl phosphate synthetase, which has two enzymatic activities, a glutamine-dependent amidotransferase and a synthase, catalyzes the formation of carbamoyl phosphate from glutamine, a bicarbonate ion, and ATP

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For reasons that are not clear, the day 3 timepoint for the MDA studies demonstrated no statistical significance, which was resolved upon day seven

doi: 10.1136/jitc-2022-005151 14 TaniTMathsyarajaHCampisiMLiZHHarataniKFaheyCGet al

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